What Are the Causes of Itching?

What Are the Causes of Itching?

Itching, physiologically; It is related to the emergence of a feeling of discomfort as a result of the stimulation of the nerve endings, which are located under the skin tissue and are responsible for the perception of sensations such as touch, pressure, vibration and pain, due to various factors. Accordingly, nerve endings are stimulated due to certain chemical substances (acids that irritate the skin or bleach, etc.), various physical conditions (temperature increase, radiation, etc.), or due to the accumulation of various substances on the skin in some diseases (accumulation of toxic substances in kidney failure, etc.). In order to suppress the feeling of discomfort that occurs with arousal, the brain targets exposing the stimulated area to a second stimulus by scratching, and itching occurs. However, long-lasting and persistent itching causes disruption of the skin’s tissue integrity and the disruption of its barrier function against foreign substances. After all, the repetitive scratching behavior can also directly damage the skin, causing re-stimulation of nerve endings and repetition of scratching.

The causes of itching can be external factors, as well as certain diseases that develop in the body. In this sense, the following ailments and factors can cause itching:

  • Dry skin: The dryness of the skin prevents the tissue from performing its duties, resulting in itching.
  • Contact dermatitis: As a result of prolonged exposure of the skin to a foreign chemical, inflammation of the skin with the reaction of the body to the chemical causes itching.
  • Allergy: An allergic reaction to various factors causes itching with skin rash and redness.
  • Chemicals: Some chemicals cause irritation when they come into contact with the skin, creating a feeling of itching.
  • Kidney failure: Harmful substances excreted from the body through the kidneys; begins to accumulate in body tissues due to kidney failure. Substances accumulating on the skin initiate an inflammatory reaction and cause itching throughout the body.
  • Infections: Local or general itching may occur as a result of exposure of the skin to viral, bacterial, fungal and parasitic infections.
  • Insect bites: Various chemical substances that enter the body through the bites of insects such as mosquitoes, bees and ticks cause itching.
  • Skin diseases: Various skin diseases such as psoriasis, lichen sclerosus, pityriasis rosea tend to develop with itching.
  • Gallbladder diseases: Accumulation of various substances, especially bilirubin, in the gallbladder or biliary tract obstructions causes itching.
  • Liver diseases: In cases that result in liver failure such as cirrhosis, harmful substances that the liver removes from the body accumulate in the body and cause widespread itching.
  • Rheumatological disorders: Various rheumatological diseases such as dermatomyositis, systemic sclerosis cause itching and other skin disorders.
  • Nervous system disorders: Some nervous system disorders that cause the destruction of nerve cells are among the causes of itching.
  • Medication side effects: Some antibiotics or pain medications are responsible for the development of itching as a result of various side effects.
  • Pregnancy-related conditions: Some health problems that occur during pregnancy and affect the hormonal system and various organs such as the skin, bile ducts and liver can bring along itching.
source: https://www.medicana.com.tr/

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